Bryan Johnson, a Silicon Valley entrepreneur known for his efforts to extend human lifespan, recently revealed he has been diagnosed with autoimmune gastritis (AIG), a chronic autoimmune condition affecting the stomach lining. Johnson, 49, said he believes there is widespread wish for his demise following the announcement of his illness.

Autoimmune gastritis causes the immune system to attack healthy stomach cells, leading to symptoms such as vitamin B12 deficiency, anemia, and an increased risk of cancer. Johnson described the condition in July on social media, stating, "My stomach is eating itself." He has been under the care of a medical team, which he employs at an annual cost of around $2 million, as part of his wider mission to combat the ageing process and extend his lifespan potentially up to 150 years.

Johnson, who has been actively pursuing biohacking and longevity treatments since about 2019, denied any connection between his condition and his experimental therapies. His regimen reportedly includes a wide range of interventions, such as numerous supplements, oral rinses with tea tree oil, and other unconventional treatments. He previously sought to reverse cellular damage through blood transfusions from his teenage son.

In an interview, Johnson speculated that he may have had autoimmune gastritis for approximately three decades. He noted that he was diagnosed with hypothyroidism at age 21 and highlighted the immunological link between thyroid and stomach conditions. He also suggested that the disease may have developed due to factors relating to an unhealthy childhood followed by weight gain in his early twenties.

Despite the diagnosis, Johnson expressed determination to continue his anti-ageing efforts. He characterized the development of the autoimmune condition as a challenge rather than a setback, saying, "I like the challenge. I’m up for it, I think it’s good timing." Johnson indicated he expected to face health obstacles over time and viewed this diagnosis as an opportunity to confront them head-on.

His comments reflect both the physical and psychological dimensions of his quest to extend human longevity through science and personalized medical interventions. While the condition presents serious health risks, Johnson remains committed to pushing the boundaries of human ageing and is prepared to manage the impacts as part of his broader mission.