Older adults who remain sexually active are encouraged to take specific precautions to reduce the risk of sexually transmitted infections (STIs), experts say. As rates of STIs continue to rise among people aged 50 and older, public health authorities underscore the importance of regular testing, open communication with partners, consistent use of barrier protection, and vaccination.

The Centers for Disease Control and Prevention (CDC) recommends that individuals undergo STI testing based on factors such as age, sexual history, practices, location, and symptoms. However, routine screening for adults over 50 is not always standard practice, so healthcare providers advise patients to proactively discuss testing with their doctors. Experts note that if couples decide to discontinue using condoms, they should first get tested together and be aware that some infections may take weeks or even months to become detectable.

Communication plays a critical role in safer sex practices. Health professionals encourage partners to have candid conversations prior to engaging in sexual activity, including questions about recent unprotected sex and the number of sexual partners within the last six months. These discussions help clarify risks and support informed decision-making.

The CDC highlights the use of condoms as the most effective barrier method against fluid-based STIs such as chlamydia, gonorrhea, and HIV. While condoms offer only partial protection against infections spread through skin-to-skin contact, dental dams and condoms are also recommended during oral sex to reduce transmission risk.

In addition to barrier methods, prophylactic medications and vaccines can provide further protection. Pre-exposure prophylaxis (PrEP) for HIV, available as a daily pill or long-acting injection, significantly lowers the risk of HIV infection. Post-exposure prophylaxis (PEP) can be effective if started within 72 hours after potential exposure. The human papillomavirus (HPV) vaccine has been approved by the U.S. Food and Drug Administration for adults up to age 45 and can help prevent HPV-related health complications.

Experts also advise avoiding sexual contact when symptoms of an STI are present. Conditions such as herpes outbreaks, syphilis sores, or genital warts may heighten the risk of transmission even if protection is used.

Transmission pathways differ depending on the infection. Fluid-based STIs are spread through contact with infected bodily fluids—vaginal fluid, semen, rectal fluid, or blood—typically during vaginal, anal, or oral sex. Skin-to-skin infections like syphilis, genital herpes, and HPV do not require the exchange of fluids and can be transmitted through direct contact with infected skin or mucous membranes, sometimes even when no symptoms are visible. Vaginal dryness, often experienced after menopause, can increase the likelihood of bleeding during sex and may elevate susceptibility to bloodborne infections.

Given these factors, health professionals emphasize regular testing, open dialogue, and preventive strategies as critical components for maintaining sexual health among older adults.