Jalen Hurts led the Philadelphia Eagles to a last-second 24-20 victory over the Tennessee Titans on Sunday in Nashville, Tennessee. With the game tied and just nine seconds remaining, Hurts connected on a 3-yard touchdown pass to Darius Cooper, capping a 65-yard drive in under two minutes. Hurts finished with 264 yards passing and two touchdowns, while receiver DeVonta Smith contributed 10 catches for 117 yards. The Eagles also benefited from Tank Bigsby’s rushing touchdown and a 58-yard field goal by Jake Elliott. The Titans’ final drive stalled at midfield, as quarterback Cam Ward’s pressured pass fell incomplete as time expired.

In Arlington, Texas, Dak Prescott broke Tony Romo’s franchise record for career touchdown passes, throwing four scores to lead the Dallas Cowboys to a 37-20 win over the Washington Commanders. Prescott’s milestone 249th touchdown was his second of the game to CeeDee Lamb, who had a team-high 153 receiving yards. The game also saw a severe injury to Commanders quarterback Jayden Daniels, who dislocated his left elbow for the second consecutive season after suffering the injury on a late incompletion as the first half ended.

The Denver Broncos ended the Jacksonville Jaguars’ nine-game regular-season winning streak with a 20-13 comeback victory at home. Jaylen Waddle was instrumental in the rally, finishing with eight catches for 138 yards after a slow start. Jonah Coleman sealed the win with a 3-yard touchdown run early in the fourth quarter, completing a 17-0 scoring run after Denver trailed 13-3 in the third quarter.

In Inglewood, California, the Las Vegas Raiders secured a 26-14 win over the Los Angeles Chargers. Kirk Cousins threw for 253 yards and three touchdowns, including a crucial 13-yard touchdown pass to Cody White that put the Raiders ahead in the third quarter. Cousins marked the milestone of his 100th NFL game in his team’s victory. Meanwhile, Chargers head coach Jim Harbaugh fell to 0-2 for the first time in his coaching career after last week’s loss to Arizona.

New Orleans Saints quarterback Tyler Shough scored on a fourth-down sneak with just over a minute left to beat the Baltimore Ravens 24-17 in Baltimore. Despite a penalty and incomplete pass that allowed Baltimore to stop the clock, the Saints elected to attempt a touchdown rather than a short field goal on fourth down, a decision upheld after review.

The Green Bay Packers overcame a 10-point deficit in the fourth quarter to defeat the New York Jets 20-17 in overtime in East Rutherford, New Jersey. Trey Smack’s 26-yard field goal in overtime secured the Packers’ first win after six consecutive losses. Key defensive plays in overtime stalled the Jets’ opening possession, allowing Green Bay to capitalize.

The Minnesota Vikings defeated the Chicago Bears 9-3 in Chicago, powered by Aaron Jones’ 105 rushing yards and three field goals from Will Reichard. Bears quarterback Caleb Williams left the game with a hamstring injury in the fourth quarter after completing 15 of 26 passes for 138 yards.

In Atlanta, the Carolina Panthers dominated the Falcons 34-3 behind Bryce Young’s 287 passing yards and three touchdowns, including two to Darren Waller. Devin Lloyd contributed defensively with a pick-six among his two interceptions in the game.

The New England Patriots secured a 20-3 win over the Pittsburgh Steelers in Foxborough, Massachusetts, fueled by Tre-Yeon Henderson’s 39-yard touchdown run in his season debut and a defensive touchdown by Eli Ponder. Pittsburgh quarterback Aaron Rodgers was held to 187 yards with one interception and four sacks.

In Houston, the Cincinnati Bengals defeated the Houston Texans 20-6 as Joe Burrow threw two touchdown passes to Ja’Marr Chase, who recorded seven catches for 75 yards. Texans quarterback C.J. Stroud completed 30 of 55 passes for 353 yards but was unable to lead his team to victory.

The Cleveland Browns edged the Tampa Bay Buccaneers 23-19 in a game delayed over two hours by lightning. Deshaun Watson threw two touchdown passes, including a key 40-yard score to Blake Whiteheart in the fourth quarter, finishing 24 of 30 for 238 yards with no turnovers.

Seattle Seahawks quarterback Drew Lock threw for 235 yards and three touchdowns in Glendale, Arizona, filling in for the injured Sam Darnold to guide Seattle past the Arizona Cardinals 31-7. Jaxon Smith-Njigba led the receiving corps with nine catches for 155 yards as Arizona’s offense struggled, totaling just 150 yards.

The San Francisco 49ers defeated the Miami Dolphins 35-13 in Santa Clara, California. Christian McCaffrey became the fourth-fastest player in the Super Bowl era to reach 100 career touchdowns, while Brock Purdy delivered a near-flawless performance. The 49ers scored touchdowns on their first five drives, asserting control throughout the game.