A student delegation from Tsinghua University’s Department of Engineering Physics visited TUM University Hospital (Klinikum rechts der Isar) in Munich on August 20 to engage with ongoing research in advanced medical imaging. The focus of the visit was on dark-field computed tomography (CT), an experimental X-ray imaging technique that differs from conventional methods by detecting small-angle scattering of X-rays rather than relying solely on differences in attenuation. This approach can provide microstructural information that may not be visible in traditional X-ray images, with potential applications including the early diagnosis of lung diseases.
The research group, led by Professor Franz Pfeiffer, explained that dark-field CT technology has not yet been widely adopted in clinical practice. Challenges include the high costs of the equipment and the need to identify the specific medical scenarios where the technology could provide the most benefit. The system remains in an exploratory phase as researchers work to define its optimal uses.
A notable aspect of the visit was learning that several graduate students in Pfeiffer’s group had assembled the dark-field imaging system themselves. For many members of the Tsinghua delegation, who were still early in their academic careers, witnessing peers construct such a complex apparatus was a significant insight into the research process. The students highlighted the importance of mastering tools like computer-aided design (CAD) software and encouraged an experimental approach summarized simply as “Just try.”
Beyond observation, the visiting students had the opportunity to participate hands-on by assembling an anthropomorphic chest phantom and operating the imaging equipment under the guidance of the graduate researchers. They were able to adjust the machinery and produce images on the computer, making the advanced medical technology tangible and more understandable than through textbooks alone.
Later in the day, Professor Daniela Pfeiffer presented clinical cases to illustrate potential applications of dark-field imaging in patient diagnosis. These real-world examples helped connect the experimental technology with the clinical challenges it aims to address.
By the end of the visit, the students gained a deeper appreciation for the iterative nature of scientific research, which involves continual questioning and problem-solving rather than simply applying known answers. The experience also shifted their perception of researchers, portraying them not only as experts but also as young individuals navigating challenges and developing solutions through learning and persistence.
For the Tsinghua delegation, the visit transformed the abstract concept of cutting-edge research into an accessible and inspiring example of innovation in medical imaging technology.