The New England Patriots handed the Buffalo Bills their first loss of the NFL season on Monday, overcoming a late fourth-quarter comeback attempt to secure a 29-26 victory in Buffalo. Patriots quarterback Drake Maye, who had struggled early in the campaign, returned to form by throwing three touchdown passes, including a decisive 23-yard one-handed catch to Efton Chism III with under two minutes remaining. This late score, followed by a two-point conversion pass to Rhamondre Stevenson, gave New England the lead. The Bills’ Josh Allen had led a promising drive earlier in the fourth quarter, connecting with Keon Coleman for a 34-yard gain that brought Buffalo ahead 26-21. However, an interception by Craig Woodson on the Bills’ next possession ended their chances of a comeback. Maye finished with 269 passing yards and 54 rushing yards, while Romeo Doubs caught two touchdowns for Buffalo, where Allen became the franchise’s all-time leader in touchdowns from scrimmage despite the loss. The Patriots improved to 2-2, while the Bills fell to 3-1.
In a closely contested matchup between unbeaten AFC West rivals, the Kansas City Chiefs edged the Las Vegas Raiders 30-27 at Allegiant Stadium, maintaining their perfect start at 4-0. Patrick Mahomes threw for 225 yards and two touchdowns, while Kenneth Walker III contributed 177 rushing yards and two touchdowns, including the go-ahead two-yard run with just over three minutes left in the game. That score followed a sensational 55-yard reception by Tyquan Thornton, who suffered a severe injury on the play, resulting in a dislocated ankle that was put back into place by team medical staff. The Raiders, now 3-1, were led by Kirk Cousins, who passed for 365 yards and two touchdowns but threw a costly interception in the final minute.
The Los Angeles Rams staged a late rally to defeat the Philadelphia Eagles 24-20. Trailing by 10 points deep in the fourth quarter, Rams running back Kyren Williams scored two touchdowns in the final four minutes, turning the contest around. Matthew Stafford orchestrated multiple scoring drives, including a 98-yard and a 79-yard march, while Eagles coach Nick Sirianni’s decision to forgo a short field goal and attempt a fourth-down conversion ultimately gave the Rams a lifeline. Both teams stand at 2-2 following the game.
Elsewhere, the San Francisco 49ers remained undefeated at 4-0 with a 24-14 victory over the Denver Broncos, aided by Brock Purdy’s two touchdown passes and Christian McCaffrey’s rushing score. The 49ers capitalized on a fumbled punt return late in the third quarter to secure the lead after a tight defensive battle.
The Dallas Cowboys came from behind to defeat the Houston Texans 34-30 in a high-scoring Texas rivalry game. CeeDee Lamb recorded a career-high 17 receptions for 189 yards and scored the winning touchdown with 40 seconds left after quarterback Dak Prescott engineered a crucial 74-yard drive, including a fourth-down conversion. Javonte Williams added three rushing touchdowns for Dallas, who improved to 2-2, while Houston remained winless.
In Baltimore, the Ravens snapped a four-game losing streak at home with a 24-18 win over the Tennessee Titans. Lamar Jackson threw for 222 yards and two touchdowns but left the game early due to an ankle injury sustained during the final play of the second quarter. The Ravens’ defense held the Titans scoreless in the second half to secure the victory, improving Baltimore to 3-1 and leaving Tennessee still searching for a first win at 0-4. Jackson was seen leaving the stadium in a protective boot after the game, though the team did not provide immediate details on his condition.