Private equity firms TPG and Blackstone are pursuing the sale of Hologic’s surgical equipment unit, seeking to raise more than $4 billion as part of efforts to reduce debt and return capital to investors following one of last year’s largest leveraged buyouts. The division focuses on manufacturing surgical devices commonly used by gynecologists, according to sources familiar with the matter.

The potential transaction is in the early stages and may attract interest from both private equity and strategic buyers, though a deal is not guaranteed. Representatives for TPG and Blackstone declined to comment.

TPG and Blackstone, alongside sovereign wealth investors Abu Dhabi Investment Authority and Singapore’s GIC, acquired Hologic in a $18.3 billion public-to-private buyout completed in April. The deal was the second-largest of its kind in the previous year, trailing only Electronic Arts’ $55 billion leveraged buyout.

The proposed sale reflects broader trends in the private equity sector, which is facing heightened pressure to return cash amid persistently high interest rates that have tempered dealmaking enthusiasm. Blackstone has notably increased capital returns over the past year, divesting nearly $50 billion through sales including broadband internet provider Hotwire, as well as initial public offerings from medical devices company Medline Industries and industrial group Legence.

In the medical technology industry, other companies are similarly evaluating sales or strategic reviews of business units. Eyecare firm CooperCompanies is conducting a strategic review that may lead to divesting its eye surgery division, while Integer Holdings, a medical device research and development outsourcer, is also exploring options.

Recent data indicate a decline in private equity’s share of overall deal activity, dropping to 21 percent in the first half of this year from 24.8 percent during the same period last year. Nonetheless, the global value of healthcare transactions surged by 83.2 percent year-on-year, reaching $271 billion, underscoring ongoing strong interest in the sector.