Negotiations between the United States and Iran aimed at resolving nuclear and related regional issues are expected to face significant challenges, according to a former British diplomat who led earlier talks with Tehran. The current 60-day dialogue marks a critical attempt to address longstanding disputes over Iran’s nuclear program, sanctions relief, and freedom of navigation in the Strait of Hormuz.

Reflecting on the experience of reaching the 2015 Joint Comprehensive Plan of Action (JCPOA), the former UK ambassador to Iran noted that those talks extended over 20 months, underscoring the technical complexity and political sensitivity inherent in such negotiations. The issues involve more than uranium enrichment limits, extending to intrusive inspections and the scope of International Atomic Energy Agency (IAEA) access to Iranian military sites. These subjects will require renewed scrutiny as parties seek more durable agreements.

Domestic politics pose additional constraints. In 2015, initial positions from both sides were rigid— the US demanded zero enrichment while Iran insisted on maintaining existing centrifuge numbers. It was only after extensive negotiations that compromises were made. Today, however, Iran’s political landscape has evolved, featuring a stronger influence of security forces, particularly the Islamic Revolutionary Guard Corps (IRGC). The IRGC’s prevailing view anticipates eventual hostilities and treats talks as tactical continuations of conflict, signaling a tougher negotiating stance focused on resilience and resistance rather than swift concessions.

Sanctions relief remains a contentious point. During the JCPOA, Iran took significant early steps like dismantling critical parts of its plutonium reactor and reducing centrifuges in exchange for economic benefits. However, inconsistent implementation and lingering caution from international businesses dampened the impact. Tehran is expected to seek reciprocal and upfront incentives in any new agreement to ensure benefits are concrete, visible, and difficult to reverse amid political shifts in Washington.

Adding complexity, more regional actors are asserting demands for involvement. Iran now leverages its position over the Strait of Hormuz as part of its deterrence strategy, affecting Gulf neighbors and global trade routes. Arab states and Israel, which views a possible agreement with skepticism, may attempt to influence or undermine negotiations perceived as threatening their security. Iran is simultaneously pursuing regional arrangements to bolster its defenses against potential Israeli offensives.

The absence of trust between Washington and Tehran continues to complicate the process. The memorandum signed on June 17 by both parties reportedly contains ambiguous language open to conflicting interpretations, raising concerns over accusations of bad faith. Previous attempts at negotiation have been disrupted by military strikes and heightened tensions, underlining the fragile nature of dialogue.

Despite these hurdles, the diplomatic engagement indicates that neither Iran nor the United States currently seeks a return to full-scale conflict. Analysts suggest the negotiation may extend beyond the initial deadline, characterized by intermittent instability and strategic maneuvering as both sides strive to secure leverage. While a protracted and imperfect deal may fall short of a final resolution, it could still represent a preferable alternative to renewed hostilities in a volatile region.