Massachusetts continues to showcase the significant influence of women leaders across a broad spectrum of industries, as highlighted in the 2026 edition of the Top 100 Women-Led Businesses list. Compiled by The Women’s Edge and featured in the Women & Power issue of Globe Magazine for the 14th consecutive year, the list underscores the growing economic impact of female-led companies within the state.
The 2026 roster includes a diverse range of enterprises, representing sectors such as health care, financial services, biotechnology, education, law, human services, and technology. Collectively, these 100 businesses reported a combined revenue and operating budget exceeding $164 billion for 2025, marking nearly a 17 percent increase compared to the previous year.
Topping the list is MassGeneralBrigham, a Boston-based health care organization led by President and CEO Anne Klibanski. Other prominent names feature Fresenius Medical Care under Helen Giza, Blue Cross Blue Shield of Massachusetts led by Sarah Iselin, Fidelity Investments with Abigail P. Johnson at the helm, Vertex Pharmaceuticals under Reshma Kewalramani, and Ropes & Gray headed by Julie H. Jones.
The methodology for the ranking incorporates multiple factors, including 2025 revenue or operating budgets, the number of full-time employees within Massachusetts, workplace and management diversity, and the implementation of innovative initiatives. The list reflects a continued commitment to recognizing women’s leadership across industries that drive the Bay State’s economy.
Additional leaders on the list include Lisa Murray of Citizens Financial Group, Sheryl McQuade of TD Bank U.S., Alexa B. Kimball of Harvard Medical Faculty Physicians, Kelly Sia of Curriculum Associates, Lisa Wieland of National Grid, Mary Ellen Coyne of J.Jill, and Susan Moffatt-Bruce of Lahey Clinic. The roster also highlights executives such as Jill Bosco of CLA, Christine Schuster of Emerson Health, Mary Anne Heino of Lantheus, Yie-Hsin Hung of State Street Investment Management, and Paula A. Johnson of Wellesley College.
Beyond corporate enterprises, the list features leaders from educational institutions and non-profit organizations, with Melissa Gilliam at Boston University, Lila Snyder at Bose, Brenda Rodriguez of Lynn Community Health Center, Marisa J. Kelly at Suffolk University, Jordina Shanks of Fenway Health, Rita M. Gardner at Melmark New England, Elyse Cherry of Blue Hub Capital, and Roberta Herman of Joslin Diabetes Center.
Overall, the annual publication highlights the pivotal role women leaders play in shaping Massachusetts’ economic landscape, reflecting increasing diversity and innovation in leadership across key industries that contribute to the state’s growth and community development.