The World Health Organization (WHO) has updated its guidelines on reducing the risk of dementia, emphasizing that up to 45 percent of cases could be prevented or delayed through changes in lifestyle and environmental factors. The agency highlighted modifiable risks including tobacco use, alcohol consumption, social isolation, physical inactivity, air pollution, and noncommunicable diseases such as hypertension and diabetes.

Dementia, which ranks as the seventh leading cause of death globally, also represents a significant source of disability and dependency among older adults. The WHO estimates that more than 57 million people worldwide are currently living with dementia, with nearly 10 million new diagnoses each year. Alzheimer's disease—the most common form of dementia—is believed to account for approximately 70 percent of cases.

In an accompanying statement, Devora Kestel, director of the WHO’s department for noncommunicable diseases and mental health, underscored the wide-reaching impact of the condition. She noted that dementia poses substantial challenges not only to health but also to the dignity, independence, and well-being of individuals, families, and communities. “This is not a distant issue; it touches all of us,” Kestel wrote in a foreword to the updated guidance published on Wednesday.

The revision builds on the organization’s first dementia recommendations released in 2019, reflecting an expanded evidence base that has informed new strategies aimed at early awareness and intervention. The guidelines seek to support healthcare providers and policymakers in implementing measures that can lessen dementia’s growing global burden as populations age.

While dementia prevalence increases significantly after age 65, the WHO emphasized that the condition is not an inevitable part of aging. “We know more today than ever before about what drives dementia risk, and these guidelines translate that knowledge into action,” said WHO Director-General Tedros Adhanom Ghebreyesus.

The updated recommendations aim to integrate dementia prevention within broader public health frameworks addressing chronic disease and environmental factors—underscoring the importance of holistic, multi-sectoral approaches to reducing risk and improving outcomes for those affected.